R Edward Hogan M D
R Edward Hogan M D - News
Edward J. Davila, of California, to be US District Judge for the Northern District of California, vice Marilyn Hall Patel, retired. Charles Bernard Day, of Maryland, to be US District Judge for the District of Maryland, vice Peter J. Messitte, retired.
What Happens After Traumatic Brain Injury Occurs
Results from a study published in the November issue of The Journal of Nuclear Medicine (JNM) show that powerful imaging techniques––positron emission tomography (PET) fused with magnetic resonance imaging (MRI)––are helping researchers better understand the long-term functional and structural changes that take place after traumatic brain injury (TBI).
"The results provide new insights into the progressive nature of the brain changes occurring following TBI, demonstrating that changes in brain structure and function after TBI are dynamic and continue to progress and evolve for months," said Viviane Bouilleret, MD, PHD, Univ Paris-Sud, one of the authors of the study, "Progressive Metabolic and Structural Cerebral Perturbations After Traumatic Brain Injury: An In Vivo Imaging Study in the Rat."
The paper reports the first study to use repeated PET and MRI of live animals to characterize the long-term progressive functional and structural brain changes that occur following experimental TBI. The model used is the lateral fluid percussion injury model in rats, the most widely utilized and validated animal model in basic TBI research. The images were assessed using a variety of sophisticated, state-of-the-art image analysis approaches.
Widespread decreases in brain functioning were seen in specific brain regions, many of which are remote from the site of direct trauma and unaccompanied by signs of injury on the MRI. The hippocampus, a brain structure critical to memory and emotion, is the key area of these changes. This may have implications for the pathophysiology of some of the long-term neurological and psychiatric morbidity, seen following TBI, even when abnormalities are not obvious on structural MRI. The severity of the neurological deficits and changes on MRI soon after the injury is predictive of severity of long-term neurodegenerative changes.
Traumatic brain injury is a leading cause of death and disability in children and young adults around the world. Long-term disabilities following TBI include: cognitive disabilities such as disorders in attention, memory, learning and executive functioning; psychiatric and behavioral problems including depression, anxiety, aggression, agitation and social inappropriateness; and epilepsy. Currently there are no effective interventions to reduce the incidence or severity of these problems.
The findings of this study indicate that secondary structural and functional changes in the brain continue to occur for many months post-TBI, which has implications for understanding the mechanisms underlying the long-term neurological and psychiatric consequences. Importantly, these findings indicate that there is a time window during which intervention could modulate these processes and mitigate against these disabling consequences of TBI.
R Edward Hogan M D - Bookshelf
Archives of neurology
Histochemical Studies FLAVIU CA ROMANUL, MD, AND EDWARD L. HOGAN, MD, ... to Neurological Unit, Boston City Hospital, Boston, Mass 02118 (Dr. Romanul). ...New York State journal of medicine
Dr. Edward J. Hogan, 308 Madison avenue, New York City. Dr. Charles Stanton James, 316 East 18tn street, New York City. Dr. Otto Maier, 316 East 18th street ...Boston medical and surgical journal
Charles Kimball Cutter, MD, MMSS, died in Somervllle, Nov. 11, 1909, aged fifty- eight years. Dr. Edward J. Hogan. an old New York practitioner, died on Nov. ...Medical and surgical reporter
John D. Hale, AB, Henry E. Handerson, Audley Ilaslett, AM, Edward J. Hogan, Geo. F. Hollick, Charles II. Horton, E Darwin Hudson, jr., AB, Edward R. Hun, ...Congressional edition
I met Strip again there, and Dennis Hogan, brother of the Police Justice Edward Hogan ; they asked me if I had registered there yet. ...Day-to-day Info Directory
R. Edward Hogan, MD :: WUSM Department of Neurology
R. Edward Hogan, MD. Dr. Hogan is the Director of the Adult Epilepsy Center. ... Bouilleret V, Hogan RE, Velakoulis D, Salzberg M, Wang L, Egan G, O'Brien TJ, Jones NC. ...
R. Edward Hogan: Neurology: Washington University Physicians ...
R. Edward Hogan, MD. Current Position. Associate Professor, Neurology ... Hogan RE, Kaiboriboon K, Osman M. Composite SISCOM images in mesial temporal lobe ...
Focus on R. Edward Hogan, MD - Washington University ...
Focus on R. Edward Hogan, MD. R. Edward Hogan is an associate professor of neurology. His ... Dr. Hogan sees patients at the Center for Advanced Medicine, ...
Adult Epilepsy :: WUSM Department of Neurology
R. Edward Hogan, MD. The adult epilepsy center specializes in the treatment of adults with ... R. Edward Hogan, MD. Samiya Rashid, DO. Luigi Maccotta, MD, PhD. Donna Theiss. Contact ...
MRI-based large deformation high dimensional mapping of the ...
Hogan, R. E., Bouilleret, V., Liu, Y. R., Wang, L., Williams, J. P., Jupp, B., Myers, D. ... Correspondence: R. Edward Hogan MD, Washington University in St. ...